Björn Eiben, Christoph Palm, Uwe Pietrzyk, Christos Davatzikos, Katrin Amunts
For accurate registration of histological sections blockface images are frequently used as three dimensional reference. However, due to the use of endocentric lenses the images suﬀer from perspective errors such as scaling and seemingly relative movement of planes which are located in diﬀerent distances parallel to the imaging sensor. The suggested correction of those errors is based on the estimation of scaling factors derived from image registration of regions characterized by diﬀering distances to the point of view in neighboring sections. The correction allows the generation of a consistent three dimensional blockface volume.