Fakultät Informatik und Mathematik
Regensburg Center for Artificial Intelligence
Regensburg Center of Biomedical Engineering
Regensburg Center of Health Sciences and Technology

Prof. Dr. rer nat. Christoph Palm

Robert Mendel, Alanna Ebigbo, Andreas Probst, Helmut Messmann, Christoph Palm

We propose an automatic approach for early detection of adenocarcinoma in the esophagus. High-definition endoscopic images (50 cancer, 50 Barrett) are partitioned into a dataset containing approximately equal amounts of patches showing cancerous and non-cancerous regions. A deep convolutional neural network is adapted to the data using a transfer learning approach. The final classification of an image is determined by at least one patch, for which the probability being a cancer patch exceeds a given threshold. The model was evaluated with leave one patient out cross-validation. With sensitivity and specificity of 0.94 and 0.88, respectively, our findings improve recently published results on the same image data base considerably. Furthermore, the visualization of the class probabilities of each individual patch indicates, that our approach might be extensible to the segmentation domain.

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